TOMO、射波刀、伽玛刀等放疗技术比较及实际使用交流贴

老马 发表于 2012-2-26 02:24

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TomoTherapy--螺旋断层放射放疗
* S* c0 |2 w' d! H  [! b螺旋断层放疗系统（TOMO）集IMRT（调强放射治疗）和IGRT（图像引导放射治疗 ...

7 {- T7 {6 i# ~, O& Z3 g弱弱的问老马，有适合巨型的放疗么

乏血供HCC，gamma刀后二月复查MRI提示肿瘤进展，此期二月未采用其它治疗手段（只吃保肝药）。

沈阳军区总医院也有一台TOMO啦，我就是做的这个，效果还是不错的

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请问各位，恶性间皮瘤可不可以作放疗？Tomo, 射波，伽玛那种合适些？

脑部放疗，上午比下午敏感许多！


7 i7 [/ v+ Y# P7 J: g& v- @Cancer 2011 Jan 15;117(2):414-20. doi: 10.1002/cncr.25423. Epub 2010 Sep 9.
Gamma knife radiosurgery for brain metastasis of nonsmall cell lung cancer: is there a difference in outcome between morning and afternoon treatment?
Rahn DA 3rd, Ray DK, Schlesinger DJ, Steiner L, Sheehan JP, O'Quigley JM, Rich T.
SourceDepartment of Radiation Oncology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA.

Abstract
BACKGROUND: Circadian cell-cycle progression causes fluctuating radiosensitivity in many tissues, which could affect clinical outcomes. The purpose of this study was to determine whether outcomes of single-session gamma knife radiosurgery (GKRS) for metastatic nonsmall cell lung cancer (NSCLC) differ based on treatment time.

4 G0 D6 y: d- `2 B" f, w5 F% tMETHODS: Fifty-eight patients received GKRS between 10:00 am and 12:30 pm and 39 patients received GKRS between 12:30 pm and 3:00 pm. The mean peripheral dose was 18.6 Gy. The mean tumor size was 7.3 cm³. Magnetic resonance imaging was used to score local control at 3 months. Cause of death (COD) was categorized as central nervous system (CNS)-related or systemic.

9 G2 c. Q8 U% s2 ]' SRESULTS: Demographic and disease characteristics of the 2 groups were similar. Local control at 3 months was achieved in 97% (35/36) of patients who underwent GKRS early in the day versus 67% (8/12) of patients who underwent GKRS later in the day (chi-square, P = .014). Early GKRS was associated with better survival (median 9.5 months) than late GKRS (median 5 months) (Kaplan-Meier log-rank test, P = .025). Factors contributing to better survival in a Cox regression model included early treatment time (P = .004) and recursive partition analysis class (P < .001). Cause of death in the early treatment group was CNS-related in 6% (3/47) of patients versus 24% (8/34) of patients in the late treatment group (chi-square test, P = .026).

# }0 n$ M7 g& e+ [' e( g; H7 hCONCLUSIONS: GKRS for metastatic NSCLC had better local control, better survival, and a lower rate of CNS-related cause of death when given earlier in the day versus later in the day. These retrospective data should encourage future study in brain radiosurgery and non-CNS stereotactic body radiotherapy series.
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常弓 发表于 2012-8-21 20:18

                               
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我们打算做伽马刀

" p, }' N4 |) L* Z/ C千万不要做伽马刀，这已经是几乎被淘汰的技术，我父亲治病时候两个病友，肺转移，都是做完伽马刀以后病情恶化很快就走了，一定要做放疗，建议做射波刀和TOMO，虽然价格相对伽马刀高昂很多，但无论从疗效精确度还是病人的副反应来说，都远胜伽马刀

我本人于2011年6月，因为头部核磁观察，原有疑似单发病灶有水肿，医生建议做头部X刀治疗，做一个头部面部磨具，当时是两天做一次，我一共照射了五次，没有任何不适感觉，治疗后至今稳定，我本人考虑头部或许不是转移病灶。

前世今生 发表于 2012-11-25 17:40

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我本人于2011年6月，因为头部核磁观察，原有疑似单发病灶有水肿，医生建议做头部X刀治疗，做一个头部面部磨 ...

照肿瘤病人的治疗规律，不管怎样，稳定就好，也不去管是否误诊了，这也是我们的悲哀

我刚做了伽马刀不久现状况还好

不错顶