刚下了avastin官网的用药指南:: r. r: B! _" W; Z$ z" h4 Y
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Patients should continue treatment until disease progression or unacceptable toxicity. a- U' O4 Y! J, ?
1 Metastatic Colorectal Cancer (mCRC) / F# Q; q/ C. e7 e) ^% I6 h
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
4 e* V* p% e4 [% p( ^6 V# {intravenous 5-FU-based chemotherapy. 0 E6 U* |& S7 l
• Administer 5 mg/kg when used in combination with bolus-IFL. & D) u/ x t) U) y3 A6 p8 `
• Administer 10 mg/kg when used in combination with FOLFOX4. 7 x$ o' p8 q% L7 w3 x O$ u! R. V9 v
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
2 ~, \; k U7 q1 w- M+ ~4 g/ y7 u The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and , p5 V4 J$ _) }' d
paclitaxel.
' H7 v7 q$ l1 O' d$ a' h3 Metastatic Breast Cancer (MBC)
. E6 N6 s- O7 {4 f M; r! B. |. { The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel. * V1 e; Y2 q/ v- T& w
4 Glioblastoma1 [/ Y9 |, m( \0 e
The recommended dose is 10 mg/kg every 2 weeks. . A/ h/ f0 s3 I. w& b! M$ u- T
5 Metastatic Renal Cell Carcinoma (mRCC)# f$ d* {" K. { H
The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa.
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! c- d( ?- A3 W按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
) t4 |' U( L( b# E! l我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |